200
| Rank | Drug | Current Manufacturer | Total Sales ($000) | % change 2008 |
| 1 | Lipitor | Pfizer Inc | 5,363,193 | -8.8% |
| 2 | Nexium | AstraZeneca Pharmaceuticals | 5,014,827 | 4.6% |
| 3 | Plavix | Bristol-Myers Squibb Company | 4,223,124 | 11.2% |
| 4 | Advair Diskus | GlaxoSmithKline | 3,653,410 | 2.3% |
| 5 (1) | Seroquel | AstraZeneca Pharmaceuticals | 3,117,591 | 7.2% |
