SENTINEL ULCER MIXTURE
Each 5 mL contains:
|Liq. Bismuth et Ammon Cit Quadruplex||0,857 mL|
|Acid Hydrochloric Dil B.P. 1968||0,054 mL|
|Vitamin B12||0,15 µg|
PHARMACOLOGICAL CLASSIFICATION :
11.10 Special Combinations
Sentinel Ulcer Mixture contains an Organic Amphoteric Bismuth Complex which has a marked astringent action on the ulcerated gastro-intestinal mucosa precipitating granulation in situ.
A proteolytic enzyme aids digestion facilitating rapid dissemination of food masses.
Treatment of Gastric Ulcers
Sensitivity to Bismuth Salts. Bismuth Salts are contraindicated in patients who have Colostomies or Ileostomies.
DOSAGE AND DIRECTIONS FOR USE:
One 5 mL medicine measureful in a small quantity of water three times daily after meals.
Shake the bottle before use.
SIDE EFFECTS AND SPECIAL PRECAUTIONS:
Sentinel Ulcer Mixture causes discoloration of the tongue.
The effects of acute Bismuth intoxication include Anorexia, Headache, Jaundice, Albuminuria and Stomatitis. Renal Failure leading to death has occured. The syndrome of Bismuth encephalopathy (confusion, tremor and impaired co-ordination) has been reported in patients with Colostomies or Ileostomies who have been given Bismuth preparations in large doses.
Bismuth preparations should not be given in large doses for a prolonged period of time. Concomitant use with alcohol should be avoided. Bismuth preparations should be used with caution in constipated patients.
KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENT:
Treatment is symptomatic. Consult nearest hospital or doctor immediately. Refer to symptoms as under “Side Effects and Special Precautions”. (Severe Bismuth intoxication may be treated with Dimercaprol. The excretion of Bismuth may be assisted by acidification of the urine with Ammonium Chloride.)
CONDITIONS OF REGISTRATION:
A deep magenta-coloured clear solution with a slight ammoniacal odour.
100 mL glass bottle with white concap.
350 mL glass bottle with black bakelite screw cap.
Store below 30°C out of direct sunlight.
Keep out of reach of children.