If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting duloxetine.
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: drugs removed from your body by certain liver enzymes (e.g., cimetidine, antipsychotics such as perphenazine, antiarrhythmics such as propafenone/flecainide/quinidine, certain quinolone antibiotics such as ciprofloxacin, antidepressants such as desipramine/fluoxetine/imipramine/paroxetine), drugs to treat high blood pressure (e.g., clonidine, guanethidine), “water pills” (diuretics such as furosemide), drugs that can cause bleeding/bruising (e.g., aspirin, antiplatelet drugs such as clopidogrel, NSAIDs such as ibuprofen, “blood thinners” such as heparin/warfarin).
Aspirin can increase the risk of bleeding when used with this medication (see above). If your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention (usually at dosages of 81-325 milligrams a day), you should continue taking it unless your doctor instructs you otherwise. Discuss the risks and benefits with your doctor.
Also tell your doctor if you take any other drugs that increase serotonin, such as buspirone, dextromethorphan, lithium, meperidine, propoxyphene, phentermine, SSRIs, other SNRIs, tryptophan, St. John’s wort, drugs used to treat migraines such as “triptans” and dihydroergotamine, street drugs such as MDMA/”ecstasy,” amphetamine. (See also Side Effects section.)
Tell your doctor or pharmacist if you also take drugs that cause drowsiness, such as certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., lorazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, quetiapine, nortriptyline, trazodone).
Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain ingredients that cause drowsiness. Dextromethorphan is a commonly used cough medication and may interact with duloxetine. Ask your pharmacist about using those products safely.
Cimetidine is a nonprescription drug that is commonly used to treat extra stomach acid. Because it may cause undesirable interactions when used with duloxetine, ask your pharmacist about other products to treat stomach acid.
This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
Cymbalta Oral Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.
NOTES:Do not share this medication with others.
Psychiatric/medical check-ups or lab tests (e.g., blood pressure, liver tests) should be done periodically to monitor your progress or check for side effects. Consult your doctor for more details.
MISSED DOSE:If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
STORAGE:Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture. Brief storage between 59-86 degrees F (15-30 degrees C) is permitted. Do not store in the bathroom. Keep all medicines away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product