Preface……………………………………. ………………………………………….. …………………….vii
Acknowledgments…………………………….. ………………………………………….. ……………..ix
Contributors……………………………….. ………………………………………….. …………………..xi
Chapter 1 Introduction to Pharmacoeconomics…………………………… ……………….1
William F. McGhan
Chapter 2 Decision Modeling Techniques…………………………………. ………………. 17
Mark S. Roberts and Kenneth J. Smith
Chapter 3 Cost of Illness……………………………………. …………………………………….37
Renée J.G. Arnold
Chapter 4 Markov Modeling in Decision Analysis…………………………………… … 47
J. Robert Beck
Chapter 5 Retrospective Database Analysis…………………………………… ………….. 59
Renée J.G. Arnold and Sanjeev Balu
Chapter 6 What Is Cost-Minimization Analysis?………………………………….. …….83
Alan Haycox
Chapter 7 Cost-Effectiveness Analysis…………………………………… ………………….95
Kenneth J. Smith and Mark S. Roberts
Chapter 8 Budget Impact Analysis…………………………………… …………………….. 109
Lieven Annemans
Chapter 9 Cost-Utility Analysis: A Case Study of a Quadrivalent Human
Papillomavirus Vaccine……………………………………. …………………….. 119
Erik J. Dasbach, Ralph P. Insinga, and Elamin H. Elbasha
Chapter 10 Some Problems/Assumptions in Pharmacoeconomic Analysis…….. 133
Stuart Birks
Chapter 11 Patient-Reported Outcome Measures…………………………………… …… 149
Dianne Bryant, Gordon Guyatt, and Renée J.G. Arnold
Chapter 12 Sensitivity Analysis…………………………………… …………………………… 163
Maarten J. Postma
Chapter 13 Use of Pharmacoeconomics in Drug Reimbursement in
Australia, Canada, and the United Kingdom: What Can We
Learn from International Experience?………………………………… ……. 175
Michael Drummond and Corinna Sorenson
Chapter 14 Pharmacoeconomics in Disease Management: Practical
Applications and Persistent Challenges…………………………………. …. 197
Ryung Suh and David Atkins
Chapter 15 Computer-Aided Decision Making from Drug Discovery to
Pharmacoeconomics…………………………… ………………………………….209
Sean Ekins and Renée J.G. Arnold
Chapter 16 Speculations on the Future Challenges and Value of
Pharmacoeconomics…………………………… ………………………………….227
J. Jaime Caro, Denis Getsios, and Rachael L. Fleurence
Index………………………………………….. ………………………………………….. ………………. 237
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