A.22.1.4 Vitamins. Other
Vitamin and mineral supplementation.
Iron salts should not be given to patients receiving repeated blood transfusions.
Copper should not be used in patients with hepatolentricular degeneration (Wilson’s disease)
Vitamin B6 reduces the effects of levodopa and this product should not be administered to patients receiving levodopa medication.
Hypervitaminosis A may occur on the administration of excessive amounts of Vitamin A over long periods.
Iron overload may occur as a result of prolonged administration of doses in excess of those recommended.
In patients receiving oral iron therapy, additional parenteral administration of iron may result in iron overloading and toxicity.
A dose of as little as 1 g of iron should be considered toxic in children.
SIDE-EFFECTS AND SPECIAL PRECAUTIONS:
Iron: Gastro-intestinal discomfort, diarrhoea, constipation and vomiting may occur.
Side-effects can be reduced by taking it with, or immediately after food.
As a result of iron therapy, stools may become darkened or black in colour.
Care should be taken when given to patients with iron storage or iron absorption diseases, haemoglobinopathies or existing gastro-intestinal disease.
The absorption of iron salts and tetracyclines is diminished when taken concomitantly by mouth.
If treatment with both is required, the iron salt should be administered three hours before or two hours after the tetracycline.
The absorption of iron salts is also decreased in the presence of antacids or when taken with tea.
Iron salts appear to reduce the effects of penicillamine.
Vitamin B6 reduces the effects of levodopa.
Vitamin C: Large doses may cause diarrhoea and other gastro-intestinal disturbances and are associated with the formation of renal calcium oxalate calculi.
Doses of 600 mg or more daily have a diuretic action.
Tolerance may be induced in patients taking high doses.
Vitamin C should be given with care to patients with hyper-oxaluria.
Patients with gout and/or a tendency to form kidney stones may be at increased risk with extended use.
Diabetics taking more than 500 mg per day may obtain false readings in their urinary glucose tests.
Zinc: Concurrent administration might diminish the effect of penicillamine.
The specific treatment of acute iron overdosage is desferroxamine.
CONDITIONS OF REGISTRATION:
As imposed by the Council.
Packs of 60 tablets
Store below 25°C